In A different factor explained herein, the peripherally acting mu-opioid receptor antagonist comprises methylnaltrexone, naltrexone, naloxone or a mix thereof. In One more aspect described herein, the peripherally acting mu-opioid receptor antagonist comprises naloxone. In One more aspect described herein, the Energetic pharmaceutical ingredient comprises hydrocodone and naloxone or ... https://jimit602mud6.sunderwiki.com/user