At present, There are 2 sorts of studies on itaconate: Irg1−/− macrophages as well as the regulatory outcome of itaconate derivatives. These two effects had been complementary and disclosed the regulatory mechanisms of itaconate concerned alkylation on Keap1 to activate Nrf2, succinate dehydrogenase inhibition, activating transcription variable 3 (ATF3) induction https://chickb232ozk5.yomoblog.com/profile