Pentobarbital will decrease the level or effect of alfentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of vincristine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of tolterodine by affecting hepatic/intest... https://socialistener.com/story5809055/considerazioni-da-sapere-su-pentobarbital-half-life